Multiple sclerosis (MS) is a chronic immune-mediated inflammatory and neurodegenerative disorder. Advances in our understanding of MS immunopathology have led to the identification of new therapeutic targets and the development of new therapies, with 16 disease-modifying therapies currently available and several additional agents in late-stage clinical development.
Most of these treatments involve the chronic use of a maintenance therapy to induce remission. However, pulsed immune reconstitution therapy (PIRT) is a treatment approach that works by either transiently or permanently resetting the immune system, with the potential to induce long-term remission or even cure.
This program will provide expert insight into the role of immune dysfunction in MS, the current treatment landscape for MS patients, and the possibility of using PIRT treatments to induce drug-free remission in MS patients.
This webcast is based on the live symposium held in San Diego, CA presented for attendees of ACTRIMS2018. It was not part of the official ACTRIMS Forum 2018.