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  Terms & Conditions                                                                                                                                     

Privacy Policy

Projects In Knowledge is committed to protecting the privacy and confidentiality of visitors to our Web site. While Projects In Knowledge does not require that you provide us with personally identifiable information in order to visit our Web site, please note that in order to participate in the continuing medical education activities that we provide, it will be necessary for you to register with us and provide this information.

About this Privacy Policy is our Web site for physicians and allied health care professionals, although it is open to non-professionals as well. The purpose of is to provide continuing medical education for healthcare professionals, and is intended for use only by a licensed healthcare professional.

Projects In Knowledge is the name we use to refer to our entire company, even though our formal corporate name is Projects In Knowledge, Inc. When we refer to ourselves as "we" or "Projects In Knowledge," we mean our company, Projects In Knowledge, Inc., including any subsidiary that we control (for example, a subsidiary that we own). We may share information among our subsidiaries that we own or control, but it is always protected under the terms of this privacy policy.

This privacy policy applies only to the Projects In Knowledge Web site. You should read the privacy policy at each Web site that you visit after you leave our site. We are not responsible for how other Web sites treat your privacy, once you leave the Projects In Knowledge site.

Privacy Policy Changes
If we change our privacy policy, we will post those changes on this page. Users should check this policy to keep abreast of any changes.

Information We Collect
In this section of our privacy policy, we discuss the different types of information we may collect about you, and the ways in which we collect them.

Information We Collect from Unregistered Visitors
Visitors to our Web site can access the Web site's home page and browse the site without disclosing any personally identifiable information. We do track information provided to us by your browser, including the Web site you came from (known as the "referring URL"), the type of browser you use, the time and date of access, and other information that does not personally identify you.

Information We Collect When You Register
Customers registering on our Web site for continuing medical education activities we provide are asked to provide us with identifying information, such as name, contact information, and other identifying information. On our registration screens, we clearly label which information is required for registration, and which information is optional and may be given at your discretion.

On our registration screens you will also find a “Burning Question” field. Submission of a “Burning Question” is completely voluntary. By submitting a “Burning Question,” you grant Projects In Knowledge the right to share it with faculty to consider as they prepare their continuing medical education presentations.

When you are using a listserve—or member-only discussion board— on our Web site, you are posting a message and your user name, which is available for all registered members to see. You should not post any information to our listserves you want to keep private. It is a condition of our Web site that when participating in a listserve, you do not:

  • Restrict or inhibit any other user from using the listserve
  • Post or transmit any unlawful, threatening, abusive, libelous, defamatory, obscene, vulgar, pornographic, profane or indecent information of any kind, including, without limitation, any transmission constituting or encouraging conduct that would constitute a criminal offense, give rise to civil liability or otherwise violate any local, state, national or foreign law
  • Post or transmit any information, software or other material which violates or infringes upon the rights of others, including material which constitutes an invasion of privacy or infringement of publicity rights or which is protected by copyright, trademark or other proprietary right, or derivative works thereof, without first obtaining permission from the owner or right holder
  • Post or transmit any information, software or other material which contains a virus or other harmful component
  • Post, or transmit, or in any way exploit any information, software or other material for commercial purposes which contains advertising, promotions or marketing

By sending a message through the listserve, you grant Projects In Knowledge the non-exclusive right and license to display, copy, publish, distribute, transmit, print, and use such information. Projects In Knowledge reserves the right to terminate your access to, and use of, the listserve if you do not abide by these conditions.

Use of Cookies
Cookies are a technology used by the Projects In Knowledge Web site to identify a user as the user moves through the Web site. Your browser allows us to place some information on your computer's hard drive that identifies the computer you are using. We use cookies to track your usage throughout our Web site.

Your Web browser can be set to allow you to control whether you will accept cookies, reject cookies, or to notify you each time a cookie is sent to you. If your browser is set to reject cookies, Web sites that are cookie-enabled will not recognize you when you return to the Web site, and some Web site functionality may be lost. The Help section of your browser will tell you how to prevent your browser from accepting cookies.

Although cookies do not normally contain personally identifiable information, if you are a registered user we may associate your registration information with cookies our Web site places on your computer's hard drive. Associating a cookie with your registration data allows us to offer increased personalization and functionality. For example, you can elect to have our Web site "remember" you and bypass the registration process each time you register for one of our educational activities. Without cookies, this functionality would not be possible. Projects In Knowledge does not currently employ cookies for this use, but is considering it to make our registration processes more efficient for you.

Children's Privacy
Projects In Knowledge's Web site is designed and intended for use by adults, and is not intended for, nor designed to be used by children under the age of 18, or any other unlicensed, untrained individuals. We do not collect personally identifiable information from any person we know is a child under the age of 18.

Uses We Make of Information
In this section of our privacy policy, we identify the ways we may use information about you that we have collected.

Aggregate Data
We create aggregate data about visitors to our Web site for activity development and improvement. We also use it for market analysis. We may provide information from our Web site in aggregate form, with identifying information removed, to third parties. For example, we may tell a third party what percentage of our registered users reside in a particular geographical area. When aggregated information is provided, we pool it from many individual records and strip it of any data that could be used to identify an individual before it is used. Any third party that receives aggregated data must agree not to attempt to re-identify the people it belongs to. Projects In Knowledge does not sell any user data to any third party for commercial purposes.

Third Parties
In addition to aggregate information (discussed previously), we may share some kinds of information with third parties as described below.

  • Business Transfers: If we transfer a business unit (such as a subsidiary) or an asset (such as a Web site) to another company, we will require them to honor the applicable terms of this privacy policy.

Protection of Information
In this section of our privacy policy, we discuss the security measures we take to protect information that we have collected about you.

General Policies
We have implemented technology and security policies, rules and other measures to protect the personal data that we have under our control from unauthorized access, improper use, alteration, unlawful or accidental destruction, and accidental loss. We also protect your information by requiring that all our employees and others who have access to or are associated with the processing of your data respect your confidentiality. In addition, we have appropriate security measures in place in our physical facilities to protect against the loss or misuse of information at our site that we have collected from you.

Projects In Knowledge Employees
Projects In Knowledge employees are required to keep customer information private, as a condition of their employment with the company. Only selected, authorized Projects In Knowledge employees are permitted to access your registration information.
Employees are required to sign a confidentiality agreement. All employees and contractors must abide by our privacy policy, and those who violate that policy are subject to disciplinary action, up to and including termination of their employment and legal action.

Privacy Questions or Concerns about Our Web Site
For privacy questions or concerns about the Projects In Knowledge Web site, please contact

Revision date: This policy was last updated on September 30, 2003.

Education Initiative in Neurology

  • Multiple Sclerosis — ECTRIMS: Cortical Lesions at MS Diagnosis Predict Secondary Progressive Disease – BreakingMED
  • The presence of cortical lesions at diagnosis in patients with multiple sclerosis proved to be strongly predictive of conversion to secondary progressive MS (SPMS) and disability in a study of patients followed for almost two decades. Having more than three cortical lesions identified by MRI at diagnosis was ... more >>
    A. Brixey, MD
  • Multiple Sclerosis — ECTRIMS: EVOLVE-MS-2 Reveals Fewer GI Events with Diroximel Fumarate – BreakingMED
  • Flushing and gastrointestinal distress are common side effects of oral fumarates used to treat multiple sclerosis, but the frequency of these events was found to be lower with diroximel fumarate than dimethyl fumarate in new data from the EVOLVE-MS-2 study.
    A. Brixey, MD
  • Multiple Sclerosis — ECTRIMS: 6-Month Natalizumab Dosing Schedule Efficacious, Study Finds – BreakingMED
  • Infusions of the disease-modifying therapy natalizumab—given every 6 weeks instead of the approved 4-week dosing schedule—proved to be efficacious in controlling multiple sclerosis (MS) disease activity, according to newly released data from the extended dosing NOVA study.
    K. Rodowicz, DO
  • Multiple Sclerosis — Some MS Drugs Attenuate Covid-19 Vaccine Response – BreakingMED
  • Some disease-modifying treatments (DMTs) used in multiple sclerosis (MS) may attenuate patients’ immune response to SARS-CoV-2 vaccination. The American Academy of Neurology (AAN) and other groups have called for vaccination for patients with neuromuscular disease and MS, regardless of immunosuppressive ... more >>
    V. Abramson, MD
  • Multiple Sclerosis — ECTRIMS: Reduced Covid-19 Response Seen in MS Patients on Some DMTs, Not Others – BreakingMED
  • Among multiple sclerosis patients on disease-modifying therapies, treatment with sphingosine-1-phosphate receptor modulators (S1P) and anti-CD20 monoclonal antibody therapies were associated with lower IgG immune response to vaccination against Covid-19 compared to treatment with other DMTs, researchers ... more >>
    A. Brixey, MD
  • ALS — Case Study: Diagnosis and Treatment of Patient with Amyotrophic Lateral Sclerosis Caused by SOD1 Mutations – @Point of Care Chapter
  • Although amyotrophic lateral sclerosis (ALS) remains an incurable disease, multidisciplinary clinics that specialize in ALS and clinical trials are refining the standard of care for patients with the disease. Patients with ALS can receive supportive care to ease symptoms and improve quality of life. In ... more >>
  • Multiple Sclerosis — Tolebrutinib Reduces New Active Brain Lesions in Relapsing MS – BreakingMED
  • As BTK inhibitors are poised to become part of the armamentarium against MS, this article looks at one of treatments under investigation—tolebrutinib—as well as the possible interactions with Covid-19 infection and vaccination.
    V. Abramson, MD
  • ALS — Amyotrophic Lateral Sclerosis: Therapies on the Horizon – @Point of Care Chapter
  • Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease. Currently, only two disease-altering therapies are approved by the FDA for the treatment of patients with ALS. Multiple downstream pathways are thought to contribute to motor neuron degeneration and offer opportunities for ... more >>
  • Multiple Sclerosis — Trial Data Support Plasma Neurofilament Light as MS Biomarker – BreakingMED
  • Blood levels of neurofilament light (NfL) in patients with relapsing multiple sclerosis (MS) on treatment were related to clinical and imaging findings, a post-hoc analysis of two phase III trials of ozanimod showed. Increased baseline plasma NfL was associated with increased gadolinium-enhancing (GdE) and T2 ... more >>
    V. Abramson, MD
  • Multiple Sclerosis — Treatment of an MS Relapse in a Patient on an S1P Modulator – @Point of Care Chapter
  • The goal of therapy in multiple sclerosis (MS) is to prevent or postpone the development of long-term disability, and reduce the impact of relapses on the patient. The concept of “no evidence of disease activity” (NEDA) is a relatively recently introduced metric used to evaluate disease-modifying therapy (DMT ... more >>
  • Alzheimer's Disease @Point of Care
  • This @Point of Care is a comprehensive, continually updated resource developed to enhance compliance to established clinical guidelines to improve screening and timely diagnosis of Alzheimer’s disease (AD) and to support current best practices of managing the symptoms of AD.
    R. Turner, MD, PhD
  • Stroke Prevention in Atrial Fibrillation and VTE @Point of Care
  • Stroke Prevention in Atrial Fibrillation and VTE @Point of Care is a clinical decision-making tool that provides a streamlined, comprehensive mobile reference for clinicians to obtain information on the diagnosis, treatment and management of Atrial Fibrillation and VTE. It is made up of a progressive series ... more >>
    S. Connolly, MD, FRCPC
  • Parkinson's Disease @Point of Care
  • From 2005 to 2030, the number of patients with Parkinson’s disease is expected to double. Caroline M. Tanner, MD, PhD provides an overview of the epidemiology of Parkinson’s disease and its associated morbidity in this subchapter of the Parkinson’s Disease @POC program.
    R. Hauser, MD, MBA
  • Multiple Sclerosis @Point of Care
  • MS @Point of Care is a clinical decision support platform that provides comprehensive information on the diagnosis, treatment and management of multiple sclerosis, made up of a progressive series of chapters and other learning tools. It provides multimedia offerings, and contextual expansion of content ... more >>
    B. Cohen, MD
    P. Coyle, MD
  • ALS — Case Study: Management of a Patient Newly Diagnosed With Amyotrophic Lateral Sclerosis – Case Study
  • Treatment options for amyotrophic lateral sclerosis (ALS) have expanded in recent years with the availability of disease-modifying and symptomatic therapies that can be offered to individuals living with ALS and have the potential to improve the quality and the length of their lives. In addition, ... more >>
    R. Bedlack, Jr, MD, PhD, FAAN
  • ALS — Neurology Morning Commute: New and Emerging Treatments for ALS – Podcast
  • In this podcast our faculty discuss new and emerging treatments for ALS, as well as managing some of the more debilitating symptoms of the disease.
    J. Shefner, MD, PhD, FAAN
  • Alzheimer's Disease — Neurology Journal Club: – Podcast
  • Is amyloid the right target for new Alzheimer’s disease therapies? Will any of these therapies, if they win approval, advance the treatment of Alzheimer’s disease? Our faculty explores these and other questions.
    B. Dickerson, MD
  • Alzheimer's Disease — Special Considerations in Neurology: – Webcast
  • Initial clinical findings from patients infected with SARS-CoV-2 suggested no risk to neuro-cognitive function, but as the world became more familiar with Covid-19, signs of neurodegenerative involvement emerged. In this exclusive video activity, Marwan Sabbagh, MD, of the Cleveland Clinic’s Lou Ruvo Center ... more >>
    M. Sabbagh, MD, FAAN
  • Alzheimer's Disease — Neurology Journal Club: – Podcast
  • Are there viable blood tests on the horizon to make diagnosis, and particularly early diagnosis, of Alzheimer’s disease possible? Our faculty takes a look at this excited field that may also enable development of better therapeutics for the disease.
  • Stroke Prevention — A Patient With a New Diagnosis of Atrial Arrhythmia Following a Recent Stent Placement – Webcast
  • Integration of patient-reported objective data, such as weight, blood pressure, and electrocardiograms, helps to provide a timely diagnosis that correlates with symptoms, as well as serves as a means of tracking arrhythmia trends over time and assessing response to therapy. Join Sanjaya Gupta, MD, FACC, FHRS, ... more >>
  • Stroke Prevention — Patient With Atrial Fibrillation at High Risk for Stroke or Thromboembolism Who Underwent Percutaneous Intervention for Acute Coronary Syndrome – Webcast
  • Patients with atrial fibrillation who undergo percutaneous intervention to treat acute coronary syndrome need highly personalized monitoring and treatment decision-making to manage the ongoing risks of stroke or thromboembolism, bleeding, and recurrent cardiac ischemic event following percutaneous ... more >>
  • Neurology Care Considerations — Neurology Journal Club – Podcast
  • How has the Covid-19 pandemic affected amyotrophic lateral sclerosis (ALS) patients? In this Journal Club podcast our faculty discusses several papers showing how the virus may affect ALS patients as well as what they are seeing in their clinics.
    R. Bedlack, Jr, MD, PhD, FAAN
  • Multiple Sclerosis — MS: Eyes on the Horizon – Podcast
  • With more than 20 disease-modifying therapies for multiple sclerosis (MS), there are still more in development. Our faculty look at what is still needed and emerging MS therapies. Moreover, they discuss how these new agents will impact clinical decision making.
  • Multiple Sclerosis — Switching Tracks in MS, Timing and Direction – Podcast
  • With the many disease-modifying therapies now available for multiple sclerosis, there are times when patients may need treatment escalated or even a lateral switch to another therapy. In this podcast, our faculty discuss assessing clinical response to these therapies and when a switch may be warranted.
    P. Coyle, MD
    J. Rinker, MD
  • ALS — Case Study: Management of a Patient Newly Diagnosed With Amyotrophic Lateral Sclerosis – Case Study
  • Treatment options for amyotrophic lateral sclerosis (ALS) have expanded in recent years with the availability of disease-modifying and symptomatic therapies that can be offered to individuals living with ALS and have the potential to improve the quality and the length of their lives. In addition, ... more >>
    R. Bedlack, Jr, MD, PhD, FAAN
  • Multiple Sclerosis — Managing RRMS Patient who Converted to SPMS – Case Study
  • This case illustrates the management of a patient who progresses from clinically isolated syndrome to relapsing multiple sclerosis (MS) and, eventually, secondary progressive MS (SPMS). It highlights treatment considerations for each stage of disease, with attention to the options that have been approved in ... more >>
    P. Coyle, MD
  • Multiple Sclerosis — Managing Highly Active Disease in an RRMS Patient with Worsening on Initial Treatment – Case Study
  • This case illustrates the treatment strategy employed for a RRMS patient who has high MS disease activity despite adherence to first-line injectable disease-modifying therapy. It highlights switching strategies that can be considered for such patients, and reviews safety and efficacy data for approved high- ... more >>
    P. Repovic, MD
  • Multiple Sclerosis — RRMS Patient with Active On-Treatment Disease Considering a Switch to a Selective Oral S1P Inhibitor – Case Study
  • In this case, the diagnosis and initial treatment of a patient with relapsing multiple sclerosis (MS) is reviewed. This illustrates the considerations that occur when a patient has a clinical relapse while on disease-modifying therapy and highlights available and emerging oral therapies for the treatment of ... more >>
    C. Azevedo, MD, MPH
  • Multiple Sclerosis — Case Study: Misdiagnosis in MS – Case Study
  • The 2017 revisions to the McDonald criteria have refined the diagnosis of multiple sclerosis (MS). However, these criteria must only be applied to patients with symptoms typical of demyelination. In addition, there must be "no better explanation." This case follows the skillful navigation of diagnosis in a 56 ... more >>
    A. Solomon, MD
  • Multiple Sclerosis — Risk-Averse RRMS Patient With a Preference for an Oral DMT – Case Study
  • This case demonstrates the real-life clinical scenario of a patient with relapsing remitting multiple sclerosis (RRMS) who has a clinical relapse on his first disease-modifying therapy. It illustrates considerations when switching medications, including patient preference for therapeutic delivery, and ... more >>
    J. Bowen, MD
  • Multiple Sclerosis — Case Study: Patient With Secondary-Progressive MS and Active Disease – Case Study
  • This case study follows a 39-year-old man who developed relapsing-remitting multiple sclerosis (MS) when he was 34. He is being treated with an oral agent for relapsing MS; however he has since advanced to secondary-progressive MS (SPMS) and shows signs of active disease radiographically. New treatment ... more >>
    E. Williamson, MD
  • Multiple Sclerosis — Patient with Active Relapsing MS at High Risk for PML – Case Study
  • This case demonstrates the real-life clinical scenario of a patient with relapsing remitting multiple sclerosis (RRMS) that is following an aggressive clinical course. It illustrates the considerations that should occur when initiating and switching disease modifying therapies (DMTs), as well as highlighting ... more >>
    P. Coyle, MD
  • Multiple Sclerosis — An African American Patient with Increasing Symptoms: Managing a Newly Diagnosed Patient with PPMS – Case Study
  • This case demonstrates the real-life clinical scenario of a patient with primary progressive multiple sclerosis (PPMS). It illustrates the considerations involved in selection of treatment for patients with progressive forms of MS, as well as highlighting the natural course of progressive disease and the ... more >>
    J. Rinker, MD
  • Multiple Sclerosis — A Patient with RRMS Who Experiences Breakthrough Disease on Two Disease-Modifying Therapies – Case Study
  • This case demonstrates the real-life clinical scenario of a patient with relapsing-remitting multiple sclerosis (RRMS) who has breakthrough disease activity on her first disease-modifying therapy (DMT) and switches to a different class of DMT. After doing well on her second DMT for awhile, she experiences ... more >>
    J. Bowen, MD

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