Projects In Knowledge - Continuing Medical Education (CME)

The Advanced Certificate Program in Breast Cancer Management III

Projects In Knowledge is pleased to present The Advanced Certificate Program: Breast Cancer Management comprised of Curricula I and II.
Curriculum I courses present a basic overview of management strategies for optimal personalized care of breast cancer patients. Curriculum II presents more advanced courses that build on new scientific developments and the topics covered in Curriculum I. Curriculum III presented by Albert Einstein College of Medicine and Projects In Knowledge provides updates on prognostic tools, newer targeted treatments, and safety of hormonal therapies and chemotherapy. It also includes case studies illustrating management decisions and treatment options for patients with refractory HER2-positive or hormone-receptor–positive metastatic breast cancer.
Featuring the very latest state-of-the-science information about breast cancer diagnosis, breast cancer treatment, and breast cancer disease management, this free online curriculum offers CME, CE, and CPE credit to oncologists and other clinicians who care for patients with breast cancer.
The curriculum courses are updated continuously throughout the year. The Advanced Certificate Program: Breast Cancer Management is building a community of experts to help you provide your patients with the best treatment outcome possible....more

H. Burstein, MD, PhD

Bridging Cultural Differences to Improve HBV Treatment in Asian and Other Diverse Communities

Adrian M. Di Bisceglie, MD, FACP, and Robert G. Gish, MD, co-chair this free, yearlong CME/CE program featuring the very latest information on screening and current and emerging treatment strategies for HBV management. Get clarity and guidance from prominent hepatology experts on key issues and practice challenges, including how cultural differences can affect physician/patient communications, thus impacting the management of HBV infection. Earn CME/CE credit and complete all courses to earn your Certificate of Advanced Study....more

A. Di Bisceglie, MD, FACP

R. Gish, MD

The Advanced Certificate Program in Multiple Sclerosis Management III

The past few years have seen exciting developments in understanding the pathophysiology and disease processes of MS and new diagnostic methodologies. Many emerging therapeutic agents are now in development with new data rapidly emerging.

The first oral therapeutics in MS have completed phase III trials and may soon become available. This outstanding free program offers you an excellent opportunity to keep current on all of these developments. Curriculum I courses present an overview of diagnostic and management strategies for MS patients, focusing on cutting-edge topics. Curriculum II presents more advanced courses that build on new scientific developments and the topics covered in Curriculum I. Curriculum III showcases important journal articles published in late 2009 through 2010, provides four new case studies featuring common clinical issues not discussed in the last two curricula, two podcasts that highlight presentations from the 2010 ECTRIMS and the 2011 AAN annual meetings, and a webcast that reviews new knowledge about potential MS risk factors and their clinical implications.

Featuring the very latest state-of-the-science information about MS diagnosis and treatment, this free online curriculum offers CME, CE, and CPE credit to neurologists and other clinicians who care for patients with MS.

New curriculum courses are continuously made available online throughout the year. Complete all courses by July 2011, and receive a certificate of advanced study.

The Advanced Certificate Program in Multiple Sclerosis Management III brings to you a community of experts to help you provide your patients with the best treatment outcomes possible....more

F. Lublin, MD

A. Miller, MD

The Advanced Certificate Program in Lung Cancer Management III

This free yearlong CME/CE program provides clinicians with up-to-date information about the management of lung cancer, featuring an expert faculty co-chaired by Roy S. Herbst, MD, PhD, and Corey J. Langer, MD, FACP, and a comprehensive curriculum of 24 web-based courses. Get timely and practical information that you can immediately use in caring for your patients with lung cancer....more

R. Herbst, MD, PhD

C. Langer, MD, FACP

The Advanced Certificate Program: Multiple Sclerosis Management II

The past few years have seen exciting developments in understanding the pathophysiology and disease processes of MS and new diagnostic methodologies. Many emerging therapeutic agents are now in development with new data rapidly emerging.

Curriculum I courses present an overview of diagnostic and management strategies for MS patients, focusing on cutting-edge topics. Curriculum II presents more advanced courses that build on new scientific developments and the topics covered in Curriculum I.

Featuring the very latest state-of-the-science information about MS diagnosis and treatment, this free online curriculum offers CME, CE, and CPE credit to neurologists and other clinicians who care for patients with MS.

New curriculum courses are continuously made available online throughout the year. Complete all courses by July 2010, and receive a certificate of advanced study....more

F. Lublin, MD

A. Miller, MD

Controversies in Targeted Therapy: Management of Recurrent Ovarian Cancer—Practical Case-Based Discussions

Projects In Knowledge is pleased to present Controversies in Targeted Therapy: Management of Recurrent Ovarian Cancer—Program Series. Featuring the very latest state-of-the-science information about practical therapeutic approaches for clinicians interested in improving outcomes in their patients with ovarian cancer – this free online program series offers CME, CE, and CPE credit. Controversies in Targeted Therapy: Management of Recurrent Ovarian Cancer—Program Series is building a community of experts to help you provide your patients with the best treatment outcome possible....more

B. Monk, MD, FACOG, FACS

The Certificate Program in Advanced/Metastatic Colorectal Cancer

Featuring the most up-to-date information available about diagnostic methods used to screen for advanced/metastatic colorectal cancer, practice guidelines, and current and emerging treatment strategies....more

L. Saltz, MD

The Advanced Certificate Program: Breast Cancer Management II.

Projects In Knowledge is pleased to present The Advanced Certificate Program: Breast Cancer Management comprised of Curricula I and II.

Curriculum I courses present a basic overview of management strategies for optimal personalized care of breast cancer patients.
Curriculum II presents more advanced courses that build on new scientific developments and the topics covered in Curriculum I.

Featuring the very latest state-of-the-science information about breast cancer diagnosis, breast cancer treatment, and breast cancer disease management, this free online curriculum offers CME, CE, and CPE credit to oncologists and other clinicians who care for patients with breast cancer.

The curriculum courses are updated continuously throughout the year.

The Advanced Certificate Program: Breast Cancer Management is building a community of experts to help you provide your patients with the best treatment outcome possible....more

H. Burstein, MD, PhD

Osteoporosis Compendium

The Osteoporosis Compendium features

Diagnostic methods used to screen for osteoporosis and osteoporosis-associated fractures
Practice guidelines
Current and emerging treatment strategies

...more

J. Levine, MD, MPH

M. Luckey, MD

E. Siris, MD

The Advanced Certificate Program in Hepatocellular Carcinoma Management

Projects In Knowledge is pleased to present The Advanced Certificate Program in Hepatocellular Carcinoma. This program offers CME and CE credit to oncologists, gastroenterologists, hepatologists, radiologists, surgeons, and other clinicians involved in the care of patients with hepatocellular carcinoma....more

G. Davis, MD

J. Geschwind, MD

Insights into Managing Leukemia & MDS Edition

What are the different types of leukemia and how can they be differentiated? What patients are at risk for the development of leukemia, and what methods are currently used to screen and diagnose these patients? What treatments are currently available for the different types of leukemia, and what agents are being developed? How is response to treatment monitored, and how can clinicians provide improved clinical outcomes for their patients with leukemia?

These are the questions addressed in Living Medical Textbook: Hematology: Insights into Managing Leukemia Edition. In each of the three chapters, an expert in oncology will focus on the incidence and pathophysiology of the various types of leukemia, including the aberrant cells involved and the molecular biologic alterations underlying these diseases; and on the methods used to treat and monitor each of the four major types of leukemia (chronic and acute lymphoid and chronic and acute myeloid), with an emphasis on current and emerging therapies. Multimedia hyperlinks will take you beyond the text to additional sources of data, information, and graphics, including conference presentations and journal articles. Please join the expert faculty for each chapter of this online and interactive "living" textbook. ...more

J. Radich, MD

Multiple Sclerosis 2010 Edition

This free, interactive CME/CE textbook provides comprehensive coverage of important MS-related topics, supplemented by hyperlinks to external multimedia resources such as illustrations, videos, journal articles, and other resources, that enhance understanding of relevant issues. ...more

B. Cohen, MD

Parkinson's Disease Edition:
Early Diagnosis and Management

Parkinson’s disease is traditionally diagnosed clinically based on classic motor symptoms of tremor, rigidity, bradykinesia, and postural instability. However, it is increasingly recognized that motor symptoms are only one manifestation of this chronic neurodegenerative disease—and a late manifestation at that. This chapter of the Parkinson's Disease Edition of the Living Medical Textbook describes the early symptoms of Parkinson’s disease, the underlying pathophysiology behind them, and available treatments for early Parkinson’s disease. Hyperlinks throughout the chapter lead the reader to more detailed and specific information on these topics from a variety of sources on the Internet in a multitude of formats. This first chapter sets the stage for a discussion of clinical trials and the neuroprotective potential of monoamine oxidase type B inhibitors in the management of early Parkinson’s disease. ...more

R. Hauser, MD, MBA

Women's Cancers Edition

More than 250,000 women will be diagnosed with breast, ovarian, cervical, or endometrial/uterine cancer this year. In each of the six chapters, an oncology expert will focus on one cancer type or stage, elucidating the current standard of care, as well as highlighting what's on the horizon with therapies in development.

Please join the expert faculty for each chapter of this online and interactive "living" textbook....more

R. Coleman, MD

M. Fornier, MD

T. Herzog, MD

B. Monk, MD, FACOG, FACS

R. Morris, MD

P. Morris, MD, MSc, MRCPI

Tumor Immunology and Immunotherapy: Metastatic Melanoma Edition

This "living" textbook is an interactive and up-to-date resource to support learning in the field of tumor immunology, and more specifically focuses on melanoma treatment and management. Chapter 1 provides a broad review of all of the cells in the innate and adaptive immune systems and briefly introduces concepts relating to the immune system's role in detecting and eliminating tumor cells. ...more

J. Weber, MD, PhD

Multiple Sclerosis — Recognizing and Treating Multiple Sclerosis in the Primary Care Setting-Case Study

Recognizing clinically isolated syndrome (CIS) and differentiating it from clinically definite multiple sclerosis poses several challenges for primary care physicians. Once a diagnosis has been made, the clinician must then decide whether or not to treat the patient and, if so, with what. The practical issues involved in diagnosing and managing CIS are illustrated in this case study of a 33-year old man presenting with numbness and tingling from his feet up to the left side of his abdomen and upper back. ...more

K. Kennedy, MN, ARNP

Osteoporosis — Experts Responding to Your Questions: Video Q&A (Fourth Quarterly Activity)

Patients with osteoporosis typically follow regimens that include nonpharmacologic and pharmacologic therapies. In this last of four installments of Experts Responding to Your Questions: Video Q&A, Dr. Nancy Lane offers practical advice on how to monitor patients for response and adherence. In addition, she describes a monitoring strategy unique to denosumab, a targeted monoclonal antibody recently approved for the treatment of postmenopausal women with osteoporosis at high risk for fracture....more

N. Lane, MD

Multiple Sclerosis — Recognizing and Treating Multiple Sclerosis in the Primary Care Setting

This CME/CE on-demand audio podcast features presentations from a recent live lecture and workshop, held in Seattle, WA, that focused on the management of multiple sclerosis (MS) in the primary care setting. Join Kate E. Kennedy, MN, ARNP, and Sylvia M. Lucas, MD, PhD, who have particular expertise in caring for patients with MS, as they discuss practical strategies on diagnosis and disease management that primary care clinicians can immediately incorporate into practice. ...more

K. Kennedy, MN, ARNP

S. Lucas, MD, PhD

Hepatitis C — Social Media, HCV, and the Gastroenterologist

I. Jacobson, MD

Osteoporosis — Experts Responding to Your Questions: Video Q&A (Third Quarterly Activity)

The status of treatment-related safety concerns, the significance of mechanism of action when choosing a bone-active agent, and the prospect of switching agents in patients with suboptimal response are just a few of the topics Dr. Paul Miller addresses in this installment of Experts Responding to Your Questions: Video Q&A.
...more

P. Miller, MD

Osteoporosis — Experts Responding to Your Questions: Video Q&A (Second Quarterly Activity)

In this second installment of Experts Responding to Your Questions: Video Q&A, join Dr. Paul Miller as he responds to your questions about risk factors for fracture and using bone mineral density to diagnose osteoporosis. ...more

P. Miller, MD

Osteoporosis — Osteoporosis: A Focus on Fracture Prevention

Although current osteoporosis therapies are effective in reducing the risk of fracture and increasing bone mineral density, all have some issues that limit their use. The GI side effects of oral bisphosphonates may preclude their use in some patients, while agents requiring intravenous or subcutaneous administration may pose problems with compliance for others. Recent advances in understanding bone remodeling and the pathophysiology of osteoporosis have led to the identification of novel therapeutic targets and the development of new emerging agents. Three experts in the field – Dolores M. Shoback, MD, Paul D. Miller, MD, and E. Michael Lewiecki, MD – discuss these important advances and their implications for the treatment of patients at risk of fracture and bone loss....more

E. Lewiecki, MD, FACP, FACE

Hepatitis C — Game Changers in Hepatology—Future Challenges in the Treatment of HCV

What will your practice look like in the coming years? Watch Game Changers in Hepatology—Future Challenges in the Treatment of HCV,, an on-demand rebroadcast of a recent CME/CE satellite symposium, chaired by Dr. Ira Jacobson, during which Rosemarie Nelson, a nationally known healthcare consultant, will interpret system-wide changes on the healthcare horizon, such as electronic medical records and new reimbursement structures, for the hepatology practice. Drs. Bruce Bacon and Nezam Afdhal will expand on how increasingly complex therapeutic regimens fit within the new healthcare paradigm.
...more

I. Jacobson, MD

Osteoporosis — Experts Responding to Your Questions: Video Q&A (First Quarterly Activity)

Do you have a clinical question you would like to ask an expert? In the first quarterly installment of Experts Responding to Your Questions: Video Q&A, Dr. Dolores Shoback answers questions from several practicing clinicians. They wanted to know about duration of therapy, the role of bone markers, safety and efficacy of new therapies, and more. Join Dr. Shoback as she shares her insights regarding these important clinical considerations. ...more

D. Shoback, MD

Osteoporosis — Update on Osteoporosis for the Rheumatologist

Rheumatologists see many patients who are at risk for secondary bone loss resulting from corticosteroid treatment and other factors, not only postmenopausal/elderly patients at risk for primary osteoporosis. In this webcast designed specifically for rheumatologists, four experts in the field discuss the pathophysiology of bone loss, the identification and diagnosis of patients at risk for primary and secondary osteoporosis, current and emerging treatment and prevention strategies for reducing fracture risk, and the challenges in managing osteoporosis patients. ...more

J. Adachi, MD, FRCPC

Leukemia — Myelodysplastic Syndromes

Although the myelodysplastic syndromes (MDS) comprise a highly heterogeneous group of clonal myeloid hematologic disorders, it is possible to stratify the disease according to progression and improve outcomes for patients with intermediate-to-high risk disease. This chapter, edited by Bart L. Scott, MD, discusses the rationale for treatment approaches now in use for MDS....more

J. Radich, MD

Breast Cancer — Expert Insight Into: The Combination of Two Anti-HER2 Monoclonal Antibodies in Patients with HER2-Positive Metastatic Breast Cancer that Progressed During Prior Therapy with One of These Agents. (Part 5 of Series)

Francisco J. Esteva, MD, PhD, reports on the encouraging results of a phase II trial of the combination of trastuzumab plus pertuzumab for the treatment of breast cancer that progressed on trastuzumab treatment. His discussion places these data in the context of preliminary results of other emerging second-line trastuzumab-containing combinations....more

F. Esteva, MD, PhD

Hepatitis B — Expert Insight Into: Severe Lactic Acidosis During Treatment of Chronic Hepatitis B with a Nucleoside Analog in Patients with Impaired Liver Function (Part 8 of Series)

Because of their high efficacy and barrier to resistance, entecavir and tenofovir are recommended for the treatment of chronic hepatitis B patients with advanced fibrosis or cirrhosis. Although these drugs have few side effects in patients with normal liver function, little is known about the side effect profiles in patients with impaired liver function. Dr. Tram Tran discusses the occurrence of lactic acidosis in a series of chronic hepatitis B patients with impaired liver function being treated with entecavir....more

T. Tran, MD

Multiple Sclerosis — Case Study: Development of Neurologic Symptoms in a Patient Treated with Disease Modifying Monoclonal Antibody Therapy

Suhayl Dhib-Jalbut, MD, describes a 45-year-old woman who develops signs and symptoms of what could be either progressive multifocal leukoencephalopathy (PML) or a new MS relapse while receiving treatment with natalizumab. Dr. Dhib-Jalbut illustrates the appropriate evaluation and workup needed to distinguish between these two diagnostic entities, and also reviews strategies for managing PML once a diagnosis is confirmed....more

F. Lublin, MD

Breast Cancer — Expert Insight Into: Initial Assessment, Surveillance, and Management of Blood Pressure in Patients Receiving VEGF Inhibitors. (Part 4 of Series)

Harold J. Burstein, MD, PhD, reports on the results of a recently published study that focused on blood pressure assessment and management in patients who take vascular endothelial growth factor (VEGF) inhibitors. Dr. Burstein’s synopsis succinctly captures the key points of this study, which presents a set of principles to guide safer use of VEGF inhibitors by individual clinicians who treat patients with cancer....more

H. Burstein, MD, PhD

Multiple Sclerosis — Recognizing and Treating Multiple Sclerosis in the Primary Care Setting-Case Study

K. Kennedy, MN, ARNP

Multiple Sclerosis — Expert Insight Into: A Prospective Open-Label Study of Endovascular Treatment of Chronic Cerebrospinal Venous Insufficiency. (Part 3 of Series)

Anne H. Cross, MD, discusses the results of the first study that explored percutaneous transluminal angioplasty (PTA) treatment of chronic cerebrospinal venous insufficiency (CCSVI), commenting on the limitations of this trial, the possible role of CCSVI in the pathogenesis of MS and the potential benefit of treating these obstructions with PTA....more

A. Cross, MD

Lung Cancer — Expert Insight Into: Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer (Part 7 of Series)

Corey J. Langer, MD, FACP, discusses results from a recent phase 2 study of stereotactic body radiation therapy for the treatment of early-stage NSCLC patients with medically inoperable peripheral tumors. The study reported encouraging results regarding overall survival rates, local tumor control, and treatment-related morbidity compared with those seen with radiation therapy and observation without specific cancer therapy, which are the conventional treatment options for these patients....more

C. Langer, MD, FACP

Breast Cancer — Expert Insight Into: Aspirin Intake and Survival After Breast Cancer (Part 3 of Series)

Lisa A. Carey, MD, ScM, reviews the recently published Aspirin Intake and Survival After Breast Cancer study, a prospective observational subgroup study of women from the Nurse’s Health Study who used aspirin after they were diagnosed with breast cancer. The results of this study are provocative but warrant further research to confirm their validity....more

L. Carey, MD, ScM

Multiple Sclerosis — Case Study: SPMS with Walking Impairment and Paroxysmal Dysarthria

Robert P. Lisak, MD, FAAN, FRCP, illustrates how to manage paroxysmal symptoms and gait impairment—two common problems in MS—in this case study of a 54-year-old physician with secondary-progressive multiple sclerosis (SPMS). Comprehensive management of MS requires attention to these symptoms, which interfere with functioning and quality of life and can persist for decades....more

A. Miller, MD