On-Demand Webcast 3
                      Updated Approaches for Treating
                      Hepatitis B


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Updated Approaches for Treating
Hepatitis B
On-Demand Webcast 3

Dear Colleague,

As a result of new therapies, updated guidelines, and data from recent studies, approaches to treating chronic hepatitis B virus (HBV) infection are evolving and being refined. Selection of an appropriate antiviral agent is critical for optimal suppression of HBV DNA in the short and long term and for prevention of treatment resistance. Initial selection of some previously standard antiviral therapies such as lamivudine may predispose patients to cross-resistance with other antivirals. It is now more important than ever that clinicians remain up-to-date about current thinking on the management of HBV infection.

We are excited that you have decided to join us for this CME/CE webcast, Updated Approaches for Treating Hepatitis B, which is part of the curriculum of the Advanced Certificate Program II: Management of Chronic Hepatitis B. This activity will provide the most current information about treatment of chronic infection with HBV, including 2006 and 2007 updates to treatment guidelines and the newest data and expert opinions regarding use of lamivudine, adefovir, entecavir, peginterferon, and telbivudine.

We are sure you will find these current perspectives helpful in furthering your care of patients infected with HBV.


Adrian M. Di Bisceglie, MD, FACP
Professor of Internal Medicine
Chief of Hepatology
Saint Louis University School of Medicine
St. Louis, Missouri

Adrian M. Di Bisceglie, MD, FACP, and Robert G. Gish, MD, co-chairs of Advanced Certificate Program II: Management of Chronic Hepatitis B, alternate to help develop content for the audioconferences. This audioconference was developed by Dr. Adrian M. Di Bisceglie and Dr. Michael W. Fried.

Kris V. Kowdley, MD
Professor of Medicine
Division of Gastroenterology/Hepatology
University of Washington Medical Center
Seattle, Washington

This activity is designed for gastroenterologists, hepatologists, and other clinicians who care for patients with hepatitis B infection or those at increased risk for acquiring the infection.

The goal of this CME/CE activity is to examine the latest information about treating chronic hepatitis B virus (HBV) infection, taking into account the most current guidelines, recent FDA approvals, and new data, in order to effectively suppress viral replication.

  • Select an appropriate antiviral agent for treating chronic HBV infection by considering current treatment guidelines and recent evidence-based data to improve patient responses.

  • Monitor HBV DNA and adjust treatment approaches based on response and development of resistance in patients with hepatitis B in order to achieve and maintain viral suppression.


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Projects In Knowledge designates this educational activity for a maximum of 1.25 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

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Adrian M. Di Bisceglie, MD, FACP, has received grant/research support from Gilead Sciences, Inc, Idenix Pharmaceuticals, Roche Pharmaceuticals, SciClone Pharmaceuticals, and Vertex Pharmaceuticals Inc; is a consultant for Abbott Laboratories, Bristol-Myers Squibb Company, Chiron Corporation, Metabasis Therapeutics, and SciClone Pharmaceuticals; is on the speakers bureau of Bristol-Myers Squibb Company, Gilead Sciences, Inc, and Roche Pharmaceuticals; and is a member of advisory boards for Bristol-Myers Squibb Company, Idenix Pharmaceuticals, Inc, Novartis Pharmaceuticals Corporation, Pharmasset, Roche Pharmaceuticals, and Vertex Pharmaceuticals Incorporated.

Kris V. Kowdley, MD, is on the speakers bureau of Gilead Sciences, Inc, and Hoffmann-La Roche Inc; and is a consultant for Bristol-Myers Squibb Company and Gilead Sciences, Inc.

Peer Reviewer has disclosed no significant relationships.

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This CME/CE activity will contain a discussion of the unlabeled/unapproved uses of emtricitabine, emtricitabine in combination with tenofovir, and tenofovir.

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This independent CME/CE activity is supported by an educational grant from Bristol-Myers Squibb Company.




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Release Date: March 1, 2007.

Termination Date: March 1, 2008.

Estimated Time for Completion of this Activity: 1.0 hour.

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  1. View the entire webcast carefully.
  2. Complete/submit the posttest and evaluation.
  3. Instantly access and print out your certificate.

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This independent CME/CE activity is supported by an educational grant from Bristol-Myers Squibb Company.

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